IL-17 signaling in host defense and inflammatory diseases

被引：0
|
作者：
Youcun Qian
Zizhen Kang
Caini Liu
Xiaoxia Li
机构：
[1] The Key Laboratory of Stem Cell Biology,Department of Immunology
[2] Institute of Health Sciences,undefined
[3] Shanghai Institutes for Biological Sciences,undefined
[4] Chinese Academy of Sciences/Shanghai Jiao Tong University School of Medicine,undefined
[5] Lerner Research Institute,undefined
[6] Cleveland Clinic,undefined
来源：
Cellular & Molecular Immunology | 2010年 / 7卷
关键词：
inflammation; interleukin-17; signaling;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Interleukin (IL)-17, the signature cytokine secreted by T helper (Th) 17 cells, plays important roles in host defense against extracellular bacterial infection and fungal infection and contributes to the pathogenesis of various autoimmune inflammatory diseases. Here we review the recent advances in IL-17-mediated functions with emphasis on the studies of IL-17-mediated signal transduction, providing perspective on potential drug targets for the treatment of autoimmune inflammatory diseases.
引用
收藏
页码：328 / 333
页数：5
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