Efficient Two-Stage Group Testing Algorithms for Genetic Screening

被引:0
|
作者
Michael Huber
机构
[1] University of Tuebingen,Wilhelm
来源
Algorithmica | 2013年 / 67卷
关键词
Group testing algorithm; Two-stage disjunctive testing; Genetic screening; DNA library; Combinatorial design;
D O I
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中图分类号
学科分类号
摘要
Efficient two-stage group testing algorithms that are particularly suited for rapid and less-expensive DNA library screening and other large scale biological group testing efforts are investigated in this paper. The main focus is on novel combinatorial constructions in order to minimize the number of individual tests at the second stage of a two-stage disjunctive testing procedure. Building on recent work by Levenshtein (Discrete Math., 266:293–309, 2003) and Tonchev (J. Comb. Optim., 15:1–6, 2008), several new infinite classes of such combinatorial designs are presented.
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页码:355 / 367
页数:12
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