Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study

被引：8

作者：

Park S.-Y. ^{[1
]}

Park Y.-W. ^{[1
]}

Ji Y.-J. ^{[2
]}

Park S.-W. ^{[3
]}

Kim S.-G. ^{[1
,4
]}

机构：

[1] Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung

[2] Department of Biomedical Engineering, Ulsan University, Ulsan

[3] Department of Electronic Engineering, Gangneung-Wonju National University, Gangneung

[4] Oral and Maxillofacial Surgery, Gangneung-Wonju National University-College of Dentistry, Gangneung

来源：

Maxillofacial Plastic and Reconstructive Surgery | / 37卷 / 1期

关键词：

Botulinum toxin type A; Electromyography; Masseter muscle; Peak voltage;

D O I：

10.1186/s40902-015-0010-8

中图分类号：

学科分类号：

摘要：

Background: The aim of this study was to investigate the effect of a botulinum toxin type A (BTX-A) injection in the masseter muscle using electromyography (EMG) in an animal model. Methods: Ten male adult (>3 months of age) New Zealand white rabbits were used. Muscle activity was continuously recorded from 8 hours before to 8 hours after BTX-A injection. The rabbits received unilateral BTX-A injections of either 5 units (group 1, n = 5) or 20 units (group 2, n = 5). Results: The masseter muscle activity of the rabbits was significantly reduced immediately after BTX-A injection (P < 0.05 for both groups). When the results from group 1 were compared with those from group 2, only the peak voltage was significantly decreased in group 2 (P = 0.013). Conclusion: Masseter muscle activity measured by EMG was immediately decreased after a BTX-A injection. © 2015, Park et al.; licensee Springer.

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