Pathophysiology of focal segmental glomerulosclerosis

被引：0
|
作者：
Kimberly Reidy
Frederick J. Kaskel
机构：
[1] Children’s Hospital at Montefiore,Division of Pediatric Nephrology
[2] Children’s Hospital at Montefiore,Division of Pediatric Nephrology
来源：
Pediatric Nephrology | 2007年 / 22卷
关键词：
Focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome; Pathophysiology; Podocyte; Injury; Animal models; Nephrin; Podocin; Transforming growth factor (TGFβ); Tubulointerstitial;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS.
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页码：350 / 354
页数：4
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