Swarm incursions of reassortants of highly pathogenic avian influenza virus strains H5N8 and H5N5, clade 2.3.4.4b, Germany, winter 2016/17

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作者：
Anne Pohlmann
Elke Starick
Christian Grund
Dirk Höper
Günter Strebelow
Anja Globig
Christoph Staubach
Franz J. Conraths
Thomas C. Mettenleiter
Timm Harder
Martin Beer
机构：
[1] Institute of Diagnostic Virology,
[2] Friedrich-Loeffler-Institut,undefined
[3] Südufer 10,undefined
[4] Institute of Epidemiology,undefined
[5] Friedrich-Loeffler-Institut,undefined
[6] Südufer 10,undefined
[7] Institute of Molecular Virology and Cell Biology,undefined
[8] Friedrich-Loeffler-Institut,undefined
[9] Südufer 10,undefined
来源：
Scientific Reports | / 8卷
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摘要：
The outbreak of highly pathogenic avian influenza H5Nx viruses in winter 2016/2017 was the most severe HPAI epizootic ever reported in Germany. The H5N8 and H5N5 viruses detected in birds in Germany in 2016/2017 represent a reassortant swarm of at least five distinct genotypes, which carried closely related HA segments derived from clade 2.3.4.4b. The genotypes of these viruses and their spatio-temporal distribution indicated a unique situation with multiple independent entries of HPAIV into Germany.
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