Production of rosmarinic acid byLavandula vera MM cell suspension in bioreactor: effect of dissolved oxygen concentration and agitation

被引：0
|
作者：
Atanas I. Pavlov
Milen I. Georgiev
Mladenka P. Ilieva
机构：
[1] Bulgarian Academy of Sciences,Department of Microbial Biosynthesis and Biotechnologies – Laboratory in Plovdiv, Institute of Microbiology
来源：
World Journal of Microbiology and Biotechnology | 2005年 / 21卷
关键词：
Agitation; bioreactor; dissolved oxygen; MM; rosmarinic acid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The relationship between dissolved oxygen (DO) concentration, agitation rate and growth of Lavandula vera MM and rosmarinic acid biosynthesis was investigated in 3 l laboratory bioreactor. Lavandula vera MM cell suspension accumulated the highest amounts of biomass (34.8 g/l) and rosmarinic acid (1870.6 mg/l) on day 12 of cultivation at 50% dissolved oxygen and agitation speed 100 rpm and at 30% dissolved oxygen and agitation speed 300 rpm, respectively.
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页码：389 / 392
页数：3
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