Preparation and drug-release behavior of β-TCP ceramics drug carrier in vitro

被引:0
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作者
Qihuan Zhang
Xin Yan
Yuhua Yan
Honglian Dai
Xin Jiang
Shipu Li
机构
[1] Yancheng Institute of Technology,College of Chemical and Biological Engineering
[2] Wuhan University of Technology,Biomedical Materials and Engineering Center
关键词
-TCP ceramics; drug carrier; physicochemical properties; drug release; clinical use;
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摘要
β-TCP ceramics drug carrier was first prepared and characterized. SEM showed that β-TCP carrier was in porous amorphous structure with diameters around 10 μm. The physical properties including apparent porosity, volume-weight, tensile strength and the permeability were measured and the results indicated those properties fit the clinical usage of β-TCP drug carrier. Furthermore, drug release experiment in vitro showed that the carrier could prolong drug release in simulated body fluid which provides basis for the clinical use of β-TCP ceramics as drug carrier.
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页码:1058 / 1060
页数:2
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