Methylation of HIV RNA has been identified as a way to modulate export of viral transcripts, thereby impacting viral gene expression and particle production. Thus epitranscriptomics adds a new layer of complexity in viral gene expression regulation and also new opportunities for developing therapeutic strategies.
机构:
MIT, Dept Biol, Howard Hughes Med Inst, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USAMIT, Dept Biol, Howard Hughes Med Inst, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA