Screening for Endophytic Fungi with Antitumour and Antifungal Activities from Chinese Medicinal Plants

被引：14
|
作者：
Haiyan Li
Chen Qing
Yanli Zhang
Zhiwei Zhao
机构：
[1] Yunnan University,Laboratory for Conservation and Utilization of Bioresources
[2] Kunming University of Science and Technology,Faculty of Biology and Chemistry Engineering
[3] Kunming Medical College,The Yunnan Key Laboratory of Pharmacology for Natural Products Research
来源：
World Journal of Microbiology and Biotechnology | 2005年 / 21卷
关键词：
Antifungal activity; antitumour activity; endophytic fungi; medicinal plants;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
One hundred and thirty endophytic fungi isolated from 12 Chinese traditional medicinal plants collected at Yuanmou county and Dawei Mountain, Yunnan province, southwest China, were tested for antitumour and antifungal activities by MTT assay on human gastric tumour cell line BGC-823 and the growth inhibition test against 7 phytopathogenic fungi. The results showed that fermentation broths from 9.2% of the isolates exhibited antitumour activity and 30% exhibited antifungal activity, moreover, some of them exhibited broad-spectrum antifungal activity. The active isolates were identified to 32 taxa. The results indicate that the endophytic fungi of Chinese traditional medicinal plants are promising sources of novel bioactive compounds.
引用
收藏
页码：1515 / 1519
页数：4
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