The rise of peripheral T helper cells in autoimmune disease

被引：0
|
作者：
Deepak A. Rao
机构：
[1] Harvard Medical School,Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital
来源：
Nature Reviews Rheumatology | 2019年 / 15卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Studies across multiple autoimmune diseases, including rheumatoid arthritis and coeliac disease, have identified a pathologically expanded PD1hiCXCR5−CD4+ T cell population that accumulates in inflamed tissues. Can this peripheral T helper cell population be harnessed as a predictive biomarker or targeted therapeutically in these diseases?
引用
收藏
页码：453 / 454
页数：1
相关论文
共 50 条
  • [21] The relationship between peripheral T follicular helper cells and disease severity in systemic sclerosis
    Sahinoglu, Melek
    Sargin, Gokhan
    Yavasoglu, Irfan
    Senturk, Taskin
    CLINICAL AND EXPERIMENTAL MEDICINE, 2024, 24 (01)
  • [22] Peripheral helper T cells in the pathogenesis of multiple sclerosis
    Hansen, Rikke Holm
    Chow, Helene Hojsgaard
    Talbot, Jacob
    Buhelt, Sophie
    Hellem, Marie Nathalie Nickelsen
    Nielsen, Jorgen Erik
    Sellebjerg, Finn Thorup
    von Essen, Marina Rode
    MULTIPLE SCLEROSIS JOURNAL, 2022, 28 (09) : 1340 - 1350
  • [23] Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases
    Yoshitomi, Hiroyuki
    Ueno, Hideki
    CELLULAR & MOLECULAR IMMUNOLOGY, 2021, 18 (03) : 523 - 527
  • [24] Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases
    Hiroyuki Yoshitomi
    Hideki Ueno
    Cellular & Molecular Immunology, 2021, 18 : 523 - 527
  • [25] Peripheral Helper T Cells in Systemic Lupus Erythematosus
    Makiyama, Asako
    Chiba, Asako
    Murayama, Goh
    Yamaji, Ken
    Tamura, Naoto
    Miyake, Sachiko
    ARTHRITIS & RHEUMATOLOGY, 2018, 70
  • [26] Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells
    J. Magarian Blander
    Miriam B. Torchinsky
    Laura Campisi
    Immunologic Research, 2012, 54 : 50 - 68
  • [27] CHARACTERIZATION OF AUTOREACTIVE HELPER T-CELLS IN A MURINE MODEL OF AUTOIMMUNE HEMOLYTIC-DISEASE
    YOUNG, JL
    HOOPER, DC
    IMMUNOLOGY, 1993, 80 (01) : 13 - 21
  • [28] Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells
    Blander, J. Magarian
    Torchinsky, Miriam B.
    Campisi, Laura
    IMMUNOLOGIC RESEARCH, 2012, 54 (1-3) : 50 - 68
  • [29] T helper 17 cell heterogeneity and pathogenicity in autoimmune disease
    Ghoreschi, Kamran
    Laurence, Arian
    Yang, Xiang-Ping
    Hirahara, Kiyoshi
    O'Shea, John J.
    TRENDS IN IMMUNOLOGY, 2011, 32 (09) : 395 - 401
  • [30] The Function of T Follicular Helper Cells in the Autoimmune Liver Diseases
    Li, Lin
    Xu, Panyang
    Zhou, Qi
    Xu, Jiancheng
    JOURNAL OF IMMUNOLOGY RESEARCH, 2020, 2020
12345