The rise of peripheral T helper cells in autoimmune disease

被引：0
|
作者：
Deepak A. Rao
机构：
[1] Harvard Medical School,Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital
来源：
Nature Reviews Rheumatology | 2019年 / 15卷
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摘要：
Studies across multiple autoimmune diseases, including rheumatoid arthritis and coeliac disease, have identified a pathologically expanded PD1hiCXCR5−CD4+ T cell population that accumulates in inflamed tissues. Can this peripheral T helper cell population be harnessed as a predictive biomarker or targeted therapeutically in these diseases?
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页码：453 / 454
页数：1
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