cis-and trans-decahydro-1,6-naphthyridines. Stereoselective synthesis and stereochemistry

被引：0
|
作者：
T. V. Esipova
A. A. Borisenko
G. V. Grishina
机构：
[1] Moscow State University,Faculty of Chemistry
来源：
Russian Journal of Organic Chemistry | 2006年 / 42卷
关键词：
Organic Chemistry; Cyanide; Hydride; Nucleophilic Addition; Stereoselective Synthesis;
D O I：
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学科分类号：
摘要：
New 1,6-disubstituted trans-decahydro-1,6-naphthyridines were synthesized by stereoselective nucleophilic addition of hydride and cyanide ions to 1,2,3,4,5,6,7,8-octahydro-1,6-naphthyridines, and their predominant conformations were determined. Some trans-decahydro-1,6-naphthyridine derivatives were found to exhibit anti-HIV activity.
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页码：922 / 928
页数：6
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