cis-and trans-decahydro-1,6-naphthyridines. Stereoselective synthesis and stereochemistry

被引：0

作者：

T. V. Esipova

A. A. Borisenko

G. V. Grishina

机构：

[1] Moscow State University,Faculty of Chemistry

来源：

Russian Journal of Organic Chemistry | 2006年 / 42卷

关键词：

Organic Chemistry; Cyanide; Hydride; Nucleophilic Addition; Stereoselective Synthesis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

New 1,6-disubstituted trans-decahydro-1,6-naphthyridines were synthesized by stereoselective nucleophilic addition of hydride and cyanide ions to 1,2,3,4,5,6,7,8-octahydro-1,6-naphthyridines, and their predominant conformations were determined. Some trans-decahydro-1,6-naphthyridine derivatives were found to exhibit anti-HIV activity.

引用

页码：922 / 928

页数：6

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