A compact microfluidic system for cell migration studies

被引：0
|
作者：
Jiandong Wu
Lipan Ouyang
Nitin Wadhawan
Jing Li
Michael Zhang
Simon Liao
David Levin
Francis Lin
机构：
[1] University of Manitoba,Department of Physics and Astronomy
[2] University of Manitoba,Department of Biosystems Engineering
[3] University of Manitoba,Department of Biological Sciences
[4] University of Manitoba,Department of Immunology
[5] University of Winnipeg,Department of Applied Computer Science
[6] Winnipeg Regional Health Authority,undefined
来源：
Biomedical Microdevices | 2014年 / 16卷
关键词：
Microfluidic systems; Cell migration; Chemotaxis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Microfluidic systems can better control cellular microenvironments and therefore are increasingly used for cell migration research. However, most existing systems are impractical to use without specialized facilities and researchers. Toward removing this barrier, we developed a compact USB microscope-based Microfluidic Chemotaxis Analysis System (UMCAS). This system integrates microfluidic devices, live cell imaging, environmental control and data analysis to provide a solution for rapid microfluidic cell migration and chemotaxis experiments with real-time result reporting. This developed system was successfully validated by testing neutrophil chemotaxis.
引用
收藏
页码：521 / 528
页数：7
相关论文
共 50 条
  • [41] Microfluidic Device with Dual Mechanical Cues for Cell Migration Investigation
    Tsai, Chin-Hsiung
    Kuo, Po-Ling
    2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2013, : 842 - 845
  • [42] Demonstration of cancer cell Migration Using a Novel microfluidic device
    Rao S.M.N.
    Lin V.K.
    Tata U.
    Raj G.V.
    Hsieh J.-T.
    Nguyen K.
    Chiao J.
    Journal of Nanotechnology in Engineering and Medicine, 2010, 1 (02)
  • [43] Microfluidic chips for the study of cell migration under the effect of chemicals
    Kukhtevich, I. V.
    Belousov, K. I.
    Bukatin, A. S.
    Chubinskiy-Nadezhdin, V. I.
    Vasileva, V. Yu
    Negulyaev, Yu A.
    Evstrapov, A. A.
    TECHNICAL PHYSICS LETTERS, 2016, 42 (05) : 478 - 481
  • [44] Computational studies of cell migration
    Jabbarzadeh, E
    Abrams, CF
    PROCEEDINGS OF THE IEEE 30TH ANNUAL NORTHEAST BIOENGINEERING CONFERENCE, 2004, : 257 - 258
  • [45] STUDIES ON STEM CELL MIGRATION
    TAKADA, A
    TAKADA, Y
    AMBRUS, IL
    KIM, U
    FEDERATION PROCEEDINGS, 1970, 29 (02) : A489 - +
  • [46] Microfluidic vascular models for studies of cell extravasation
    Lehtonen, Janne
    Persson, Henrik
    Svensson, Lena
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2017, 86 (04) : 313 - 313
  • [47] Flow-based compact microfluidic electrochemical cell with Parafilm® channels
    Li, Zhenglong
    Haridas, Niranjan
    Rahman, Maryom
    Kaaliveetil, Sreerag
    Cheng, Yu-Hsuan
    Chande, Charmi
    Basuray, Sagnik
    ELECTROCHIMICA ACTA, 2023, 470
  • [48] Compact Poly/Monochromatic Colorimetric Sensing System With Integrated Microfluidic Sampler
    Lachance, Gabriel P.
    Chamelot, Guillaume
    Morin, Jean-Francois
    Boisselier, Elodie
    Boukadoum, Mounir
    Miled, Amine
    IEEE SENSORS JOURNAL, 2024, 24 (22) : 37666 - 37677
  • [49] A Compact Control System to Enable Automated Operation of Microfluidic Bioanalytical Assays
    Gonzalez-Suarez, Alan M. M.
    Long, Alexander
    Huang, XuHai
    Revzin, Alexander
    BIOSENSORS-BASEL, 2022, 12 (12):
  • [50] Automated microfluidic compact disc (CD) cultivation system of Caenorhabditis elegans
    Kim, Nahui
    Dempsey, Catherine M.
    Zoval, Jim V.
    Sze, Ji-Ying
    Madou, Marc J.
    SENSORS AND ACTUATORS B-CHEMICAL, 2007, 122 (02) : 511 - 518
12345