The direct effect of Focal Adhesion Kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis

被引：0
|
作者：
Vita M Golubovskaya
Min Zheng
Li Zhang
Jian-Liang Li
William G Cance
机构：
[1] Roswell Park Cancer Institute,Department of Surgical Oncology
[2] UF Shands Cancer Center,undefined
[3] Interdisciplinary Center for Biotechnology Research,undefined
来源：
BMC Cancer | / 9卷
关键词：
Doxycycline; Focal Adhesion Kinase; Breast Tumorigenesis; Focal Adhesion Kinase Expression; Focal Adhesion Kinase Signaling;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 29 条
  • [21] High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome
    Klaus Jürgen Schmitz
    Florian Grabellus
    Rainer Callies
    Friedrich Otterbach
    Jeremias Wohlschlaeger
    Bodo Levkau
    Rainer Kimmig
    Kurt Werner Schmid
    Hideo Andreas Baba
    Breast Cancer Research, 7
  • [22] High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome
    不详
    PATHOLOGY RESEARCH AND PRACTICE, 2005, 201 (03) : 217 - 217
  • [23] Focal adhesion kinase (FAK) mediates fibroblast-induced HER2+breast cancer cell migration and invasion through a mechanism involving Stat3
    Lazaro, Glorianne
    Smith, Chris
    Hiscox, Stephen
    CANCER RESEARCH, 2014, 74 (19)
  • [24] Inhibition of vascular endothelial growth factor receptor-3 (VEGFR-3) binding to focal adhesion kinase (FAK) causes apoptosis in human breast cancer cells
    Garces, CA
    Kurenova, EV
    Golubovskaya, VM
    Beierle, EA
    Cance, WG
    ANNALS OF SURGICAL ONCOLOGY, 2005, 12 (02) : S10 - S10
  • [25] Synergistic activity of focal adhesion kinase (FAK) and epidermal growth factor receptor (EGFR) in the cellular effects induced in human breast carcinoma BT-474 cells by AdFAK-CD.
    Beviglia, L
    Xu, LH
    Earp, HS
    Cance, WG
    MOLECULAR BIOLOGY OF THE CELL, 2000, 11 : 29A - 29A
  • [26] Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)
    Rigiracciolo, Damiano Cosimo
    Nohata, Nijiro
    Lappano, Rosamaria
    Cirillo, Francesca
    Talia, Marianna
    Adame-Garcia, Sendi Rafael
    Arang, Nadia
    Lubrano, Simone
    De Francesco, Ernestina Marianna
    Belfiore, Antonino
    Gutkind, J. Silvio
    Maggiolini, Marcello
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2022, 41 (01)
  • [27] Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)
    Damiano Cosimo Rigiracciolo
    Nijiro Nohata
    Rosamaria Lappano
    Francesca Cirillo
    Marianna Talia
    Sendi Rafael Adame-Garcia
    Nadia Arang
    Simone Lubrano
    Ernestina Marianna De Francesco
    Antonino Belfiore
    J. Silvio Gutkind
    Marcello Maggiolini
    Journal of Experimental & Clinical Cancer Research, 41
  • [28] A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.13,7]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo
    Golubovskaya, Vita M.
    Figel, Sheila
    Ho, Baotran T.
    Johnson, Christopher P.
    Yemma, Michael
    Huang, Grace
    Zheng, Min
    Nyberg, Carl
    Magis, Andrew
    Ostrov, David A.
    Gelman, Irwin H.
    Cance, William G.
    CARCINOGENESIS, 2012, 33 (05) : 1004 - 1013
  • [29] Blockage of MDR1 gene expression by dominant inhibition of cyclic AMP-dependent protein kinase in adriamycin-resistant human MCF-7 breast cancer cells
    Parissenti, AM
    Gannon, BR
    Chadderton, A
    Glück, S
    FASEB JOURNAL, 1997, 11 (09): : A1449 - A1449
123