Biocompatibility of Biodegradable Polymer Films Based on Poly(lactic-co-glycolic acid) of Various Molecular Weights

被引：0
|
作者：
Baikin A.S. [1 ]
Sevost’yanov M.A. [1 ]
Nasakina E.O. [1 ]
Sergienko K.V. [1 ]
Kaplan M.A. [1 ]
Konushkin S.V. [1 ]
Kolmakova A.A. [1 ]
Yakubov A.D. [1 ]
Bunkin N.F. [2 ,3 ]
Gudkov S.V. [3 ,4 ,5 ]
Shatova L.A. [6 ]
Barinov S.M. [1 ]
Kolmakov A.G. [1 ]
机构：
[1] Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Moscow
[2] Bauman Moscow State Technical University, Moscow
[3] Prokhorov General Physics Institute, Moscow
[4] Lobachevsky State University of Nizhny Novgorod—National Research University, Nizhny Novgorod
[5] Moscow Regional Research Clinical Institute, Moscow
[6] Voronezh State Technical University, Voronezh
来源：
Inorganic Materials: Applied Research | 2019年 / 10卷 / 04期
关键词：
biocompatibility; biodegradable materials; poly(lactic-co-glycolic acid); polymer films; superelasticity;
D O I：
10.1134/S207511331904004X
中图分类号：
学科分类号：
摘要：
Abstract: Various poly(lactic-co-glycolic acid)-based polymeric films with various molecular weights were obtained. The mechanical characteristics of these films were investigated. It was shown that the obtained polymer films do not have a short-term toxic effect on mammalian cells. The percentage of actively dividing cells on such polymer films is 1.5–3.0 times higher than when grown on culture glass, and, accordingly, the cell layer is formed faster. The obtained poly(lactic-co-glycolic acid)-based polymer films are biocompatible. © 2019, Pleiades Publishing, Ltd.
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页码：887 / 891
页数：4
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