New bone-forming treatments for osteoporosis

被引：0
|
作者：
Socrates E. Papapoulos
机构：
[1] Center for Bone Quality,
[2] Leiden University Medical Center,undefined
来源：
Nature Reviews Endocrinology | 2015年 / 11卷 / 2期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In 2014, two phase II clinical studies reported rapid, impressive increases in BMD in women with low bone mass who were treated with sclerostin inhibitors for 1 year. The antifracture efficacy and tolerability of these new, bone-building therapies are currently being investigated in phase III clinical trials.
引用
收藏
页码：69 / 70
页数：1
相关论文
共 50 条
  • [31] GLUCOCORTICOIDS AND BONE METABOLISM: IDENTIFYING NEW PLAYERS IN THE NEGATIVE IMPACT OF GLUCOCORTICOIDS ON BONE-FORMING CELLS
    Ali, Dalia
    Madsen, Martin R.
    Kassem, Moustapha
    Mandrup, Susanne
    Rauch, Alexander
    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2024, 79 (05): : 3 - 3
  • [32] CARTILAGE-FORMING AND BONE-FORMING TUMORS OF THE SOFT-TISSUES
    REIMAN, HM
    DAHLIN, DC
    SEMINARS IN DIAGNOSTIC PATHOLOGY, 1986, 3 (04) : 288 - 305
  • [33] A novel economic framework to assess the cost-effectiveness of bone-forming agents in the prevention of fractures in patients with osteoporosis
    Soreskog, E.
    Borgstrom, F.
    Lindberg, I.
    Strom, O.
    Willems, D.
    Libanati, C.
    Kanis, J. A.
    Stollenwerk, B.
    Charokopou, M.
    OSTEOPOROSIS INTERNATIONAL, 2021, 32 (07) : 1301 - 1311
  • [34] Osteoblast function and the mechanism of action of bone-forming agents
    Mundy, GR
    OSTEOPOROSIS 1996, 1996, 1118 : 17 - 28
  • [35] A novel economic framework to assess the cost-effectiveness of bone-forming agents in the prevention of fractures in patients with osteoporosis
    E. Söreskog
    F. Borgström
    I. Lindberg
    O. Ström
    D. Willems
    C. Libanati
    J. A. Kanis
    B. Stollenwerk
    M. Charokopou
    Osteoporosis International, 2021, 32 : 1301 - 1311
  • [36] Bone-forming capacity of adult human nasal chondrocytes
    Pippenger, Benjamin E.
    Ventura, Manuela
    Pelttari, Karoliina
    Feliciano, Sandra
    Jaquiery, Claude
    Scherberich, Arnaud
    Walboomers, X. Frank
    Barbero, Andrea
    Martin, Ivan
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2015, 19 (06) : 1390 - 1399
  • [37] Adiponectin and its receptors are expressed in bone-forming cells
    Berner, HS
    Lyngstadaas, SP
    Spahr, A
    Monjo, M
    Thommesen, L
    Drevon, CA
    Syversen, U
    Reseland, JE
    BONE, 2004, 35 (04) : 842 - 849
  • [38] PRIMARY BONE-FORMING TUMOURS AND THEIR RELATIONSHIP TO SKELETAL GROWTH
    PRICE, CHG
    JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1958, 40 (03): : 574 - 593
  • [39] Bone-forming agents in non-responders to bisphosphonates
    Compston, Juliet
    LANCET, 2017, 390 (10102): : 1565 - 1566
  • [40] Benign bone-forming tumors [Gutartige knochenbildende tumoren]
    Heuck A.
    Stäbler A.
    Wörtler K.
    Steinborn M.
    Der Radiologe, 2001, 41 (7): : 540 - 547
12345