Adjuvant endocrine therapy for premenopausal women with early breast cancer

被引：0
|
作者：
Ting Bao
Nancy E Davidson
机构：
[1] Johns Hopkins University,Sidney Kimmel Comprehensive Cancer Center
来源：
Breast Cancer Research | / 9卷
关键词：
Tamoxifen; Endocrine Therapy; Premenopausal Woman; GnRH Agonist; Exemestane;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Adjuvant endocrine therapy is a pivotal component of treatment for premenopausal women with early-stage hormone receptor-positive breast cancer. Currently, the standard endocrine therapy for premenopausal women is tamoxifen; a role for ovarian suppression or ablation has also been identified. Uncertainty remains about the optimal use of endocrine therapy in this setting. The role of ovarian suppression with tamoxifen or aromatase inhibitor, the optimal duration of adjuvant endocrine therapy and the utility of biomarkers and pharmacogenetic studies to select therapy are questions worthy of further investigation.
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