Synthesis and fungicidal activity of alkyl(aryl)-substituted 1,3,4-thiadiazolidines

被引：0
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作者：
V. R. Akhmetova
N. N. Makhmudiyarova
I. S. Bushmarinov
G. R. Khabibullina
N. F. Galimzyanova
机构：
[1] Russian Academy of Sciences,Institute of Petrochemistry and Catalysis
[2] Russian Academy of Sciences,A. N. Nesmeyanov Institute of Organoelement Compounds
[3] Russian Academy of Sciences,Institute of Biology, Ufa Scientific Center
来源：
Chemistry of Heterocyclic Compounds | 2013年 / 49卷
关键词：
aldehydes; hydrogen sulfide; substituted hydrazines; 1,3,4-thiadiazolidine; fungicidal activity; cyclothiomethylation;
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摘要：
3,3'-Methanediylbis(4-methyl-1,3,4-thiadiazolidine) has been obtained through the cyclothio-methylation of methylhydrazine, formaldehyde, and H2S. A series of 2,5-dialkyl(aryl)-3-phenyl(benzyl)-1,3,4-thiadiazolidines has been synthesized through cyclothiomethylation of phenyl(benzyl)hydrazines with aliphatic and aromatic aldehydes and H2S. The fungicidal activity of 2,5-dimethyl-3-phenyl-1,3,4-thia-diazolidine relative to Bipolaris sorokiniana and Fusarium oxysporum has been observed, so as for the water-soluble adduct of methyl iodide and 2,5-dimethyl-3-phenyl-1,3,4-thiadiazolidine relative to Bipolaris sorokiniana.
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页码：1224 / 1231
页数：7
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