Good vibrations in enzyme-catalysed reactions

被引：0
|
作者：
Sam Hay
Nigel S. Scrutton
机构：
[1] Manchester Interdisciplinary Biocentre,
[2] University of Manchester,undefined
来源：
Nature Chemistry | 2012年 / 4卷 / 3期
关键词：
D O I：
10.1038/nchem.1223
中图分类号：
学科分类号：
摘要：
This Perspective discusses contemporary ideas for enzymatic reactions that invoke a role for fast 'promoting' (or 'compressive') motions or vibrations that, in principle, can facilitate enzyme-catalysed reactions. With an emphasis on hydrogen-transfer reactions, experimental, theoretical and computational approaches that have lent evidence to this controversial hypothesis are discussed.[graphic not available: see fulltext]
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页码：161 / 168
页数：7
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