Immunosignatures associated with TP53 status and co-mutations classify prognostically head and neck cancer patients

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作者
Andrea Sacconi
Paola Muti
Claudio Pulito
Giulia Urbani
Matteo Allegretti
Raul Pellini
Nikolay Mehterov
Uri Ben-David
Sabrina Strano
Paolo Bossi
Giovanni Blandino
机构
[1] Clinical Trial Center,Department of Biomedical
[2] Biostatistics and Bioinformatics,Translational Oncology Research Unit
[3] IRCCS Regina Elena National Cancer Institute,Department of Medical Biology
[4] Surgical Science and Oral Health,Research Institute
[5] Milan University,Department of Human Molecular Genetics and Biochemistry
[6] Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico,Department of Biomedical Sciences
[7] Maxillo-Facial Surgery and Dental Unit,undefined
[8] IRCCS Regina Elena National Cancer Institute,undefined
[9] Otolaryngology Head and Neck Surgery Unit,undefined
[10] IRCCS Regina Elena National Cancer Institute,undefined
[11] Medical University-Plovdiv,undefined
[12] Medical University-Plovdiv,undefined
[13] Faculty of Medicine,undefined
[14] Tel Aviv University,undefined
[15] SAFU Unit,undefined
[16] IRCCS Regina Elena National Cancer Institute,undefined
[17] Humanitas University,undefined
[18] IRCCS Humanitas Research Hospital,undefined
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关键词
HNSCC; Immunotherapy; Immune checkpoint inhibitor; p53; PDL1; c-MYC; PI3K;
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