Physicochemical Investigations on Solid Lipid Nanoparticles and on Oil-Loaded Solid Lipid Nanoparticles: A Nuclear Magnetic Resonance and Electron Spin Resonance Study

被引：0
|
作者：
Katja Jores
Wolfgang Mehnert
Karsten Mäder
机构：
[1] Free University of Berlin,Institute of Pharmacy, Department of Pharmaceutical Technology
[2] Martin-Luther-University Halle-Wittenberg,Institute of Pharmaceutical Technology and Biopharmacy
[3] Wolfgang-Langenbeck-Str. 4,undefined
来源：
Pharmaceutical Research | 2003年 / 20卷
关键词：
solid lipid nanoparticles; colloidal carrier; nanoemulsion; ESR; NMR; SLN; NLC;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. Recently, colloidal dispersions made of mixtures from solid and liquid lipids have been described to combine controlled-release characteristics with higher drug-loading capacities than solid lipid nanoparticles (SLNs). It has been proposed that these nanostructured lipid carriers (NLCs) are composed of oily droplets that are embedded in a solid lipid matrix. The present work investigates the structure and performance of NLCs.
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页码：1274 / 1283
页数：9
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