Aspartic acid as a highly efficient and nontoxic organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions
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作者:
A. Ghorbani-Choghamarani
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机构:Ilam University,Department of Chemistry, Faculty of Science
A. Ghorbani-Choghamarani
M. Hajjami
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机构:Ilam University,Department of Chemistry, Faculty of Science
M. Hajjami
F. Gholamian
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机构:Ilam University,Department of Chemistry, Faculty of Science
F. Gholamian
G. Azadi
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机构:Ilam University,Department of Chemistry, Faculty of Science
G. Azadi
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[1] Ilam University,Department of Chemistry, Faculty of Science
Aspartic acid was found to be an efficient organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions. The remarkable advantages offered by this method are the inexpensive and green catalyst, mild reaction conditions, simple procedures, and excellent yield of products.