One-pot synthesis of tri- and tetra-substituted imidazoles using sodium dihydrogen phosphate under solvent-free conditions

被引：0

作者：

Zahed Karimi-Jaberi ^{[1
]}

Mohammad Barekat ^{[1
]}

机构：

[1] Department of Chemistry,Islamic Azad University

来源：

ChineseChemicalLetters | 2010年 / 21卷 / 10期

关键词：

Sodium dihydrogen phosphate; Imidazoles; Benzil; Solvent-free;

D O I：

暂无

中图分类号：

O614.112 [钠Na];

学科分类号：

摘要：

Sodium dihydrogen phosphate（NaH;PO;） efficiently catalyzes the condensation reaction of benzil,aldehydes,amines and ammonium acetate in a four-component reaction under solvent-free conditions.The reaction proceeds rapidly and affords the corresponding tetra-substituted imidazoles in high yields.Also an efficient route was developed for the synthesis of tri-substituted imidazoles from condensation of benzil,aldehydes and ammonium acetate using NaH;PO;.

引用

页码：1183 / 1186

页数：4

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