Reverse remodeling in heart failure—mechanisms and therapeutic opportunities

被引:0
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作者
Norimichi Koitabashi
David A. Kass
机构
[1] Gunma University Graduate School of Medicine,Department of Medicine and Biological Sciences
[2] Johns Hopkins Medical Institutions,Division of Cardiology, Department of Medicine
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摘要
Understanding mechanisms of cardiac remodeling, with the goal of developing therapies to stop or reverse its progression, has become a major objective for investigators of heart failure. In this Review, Dr Koitabashi and Professor Kass discuss the evidence for 'reverse remodeling' by existing therapies, and review novel approaches that are currently moving from preclinical to clinical trials.
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页码:147 / 157
页数:10
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