Synthesis and Fluorescence Properties of new Monastrol Analogs Conjugated Fluorescent Coumarin Scaffolds

被引：0
|
作者：
Najim A. Al-Masoudi
Niran J. Al-Salihi
Yossra A. Marich
Timo Markus
机构：
[1] University of Basrah,Department of Chemistry, College of Science
[2] Am Tannenhof 8,Department of Chemistry
[3] University of Konstanz,undefined
来源：
Journal of Fluorescence | 2016年 / 26卷
关键词：
Biginelli reaction; Coumarins; MPA supported on Y zeolite; Monastrol; Fluorescence properties;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A mild and efficient method has been used for the synthesis of ethyl 4-(3-hydroxphenyl)-6-methyl-2-thioxo-1,3-dihydroprimidine-5-carboxylate (monastrol) (2), via Biginelli reaction. Alkylation of 2 with the fluorescent coumarin 3 afforded the new thioether analog 4. Similarly, ethyl 4-(6,8-dichloro-2-oxo-2 H-chromen-3-yl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylate (6) was prepared. The synthesized compounds are fluorescent active and show wavelength of maximum absorption (λmax) in UV or visible region in MeOH at room temperature.
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页码：31 / 35
页数：4
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