Safety Considerations with Bisphosphonates for the Treatment of Osteoporosis

被引：0
|
作者：
William Strampel
Ronald Emkey
Roberto Civitelli
机构：
[1] Michigan State University College of Osteopathic Medicine,
[2] Emkey Arthritis and Osteoporosis Clinic,undefined
[3] Washington University School of Medicine,undefined
来源：
Drug Safety | 2007年 / 30卷
关键词：
Bisphosphonates; Alendronate; Zoledronic Acid; Osteonecrosis; Risedronate;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Bisphosphonates are the most commonly prescribed medications for the treatment of osteoporosis. Although evidence supports a good safety profile for these agents, numerous tolerability issues have been associated with their use. This review provides an overview of the safety issues associated with the nitrogen-containing class of bisphosphonates and discusses the potential effect of these issues on adherence. The review specifically considers upper gastrointestinal (UGI) adverse events (AEs), renal toxicity, influenza-like illness, osteonecrosis of the jaw and evidence on how to treat or prevent these events.
引用
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页码：755 / 763
页数：8
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