Active defense under oxidative stress. The antioxidant responsive element

被引：0

作者：

V. V. Lyakhovich

V. A. Vavilin

N. K. Zenkov

E. B. Menshchikova

机构：

[1] Siberian Branch of the Russian Academy of Medical Sciences,Institute of Molecular Biology and Biophysics

[2] Siberian Branch of the Russian Academy of Medical Sciences,Scientific Center of Clinical and Experimental Medicine

来源：

Biochemistry (Moscow) | 2006年 / 71卷

关键词：

oxidative stress; antioxidant responsive element;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

This review considers the mechanisms and factors that stimulate transcription of genes regulated by the antioxidant responsive element (ARE). The latter is important for cell defense under conditions of oxidative stress and also for detoxification of electrophilic xenobiotics. There are differences in regulation of intracellular homeostasis involving Nrf2-mediated activation of ARE and other redox-sensitive factors (NF-κB and AP-1).

引用

页码：962 / 974

页数：12

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