Synthesis and properties of 3-amino-2-(2-benzimidazolyl)-δ2-pyrrolizidin-1-one

被引:0
|
作者
Volovenko Yu.M. [1 ]
机构
[1] Taras Shevchenko Kiev University
关键词
Chloride; Organic Chemistry; Benzimidazole; Acid Chloride; Protective Group;
D O I
10.1007/BF02253040
中图分类号
学科分类号
摘要
2-Benzimidazotylacetonitrile is acetylated by the acid chloride derivative of N-trifluoroacetylproline to give N- and C-acyl derivatives. Removal of the trifluoroacetyl protective group in the C-acyl derivatives is accompanied by cyclization to give 3-amino-2-(2-benzimidazolyl)-Δ2-pyrrolizidin-1-one. Exhaustive acylation of this product gives a derivative of a new heterocyclic system, namely, pyrrolizino[3′,2′:5,6]-pyrimido[3,4-a] benzimidazole. ©1998 Plenum Publishing Corporation.
引用
收藏
页码:854 / 856
页数:2
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