BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells

被引:0
|
作者
Rui Song
David A. Fullerton
Lihua Ao
Daniel Zheng
Ke-seng Zhao
Xianzhong Meng
机构
[1] University of Colorado Denver,Department of Surgery
[2] Southern Medical University,Department of Pathophysiology
来源
Journal of Molecular Medicine | 2015年 / 93卷
关键词
BMP-2; TGF-β1; Biglycan; Aortic valve; Osteogenic responses;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:403 / 412
页数:9
相关论文
共 50 条
  • [21] ERK1/2 drives IL-1β-induced expression of TGF-β1 and BMP-2 in torn tendons
    Wataru Morita
    Sarah J. B. Snelling
    Kim Wheway
    Bridget Watkins
    Louise Appleton
    Andrew J. Carr
    Stephanie G. Dakin
    Scientific Reports, 9
  • [22] Frequent immunoexpression of TGF-β1, FGF-2 and BMP-2 in fibroblast-like cells in osteofibrous dysplasia
    Sakamoto, Akio
    Oda, Yoshinao
    Iwamoto, Yukihide
    Tsuneyoshi, Masazumi
    ONCOLOGY REPORTS, 2007, 17 (03) : 531 - 535
  • [23] Mechanisms of serotonin induced valve disease:: Serotonin causes TGF-β upregulation and increased phospholipase C activity in aortic valve interstitial cells
    Jian, B
    Liang, BT
    Levy, RJ
    CIRCULATION, 2000, 102 (18) : 116 - 116
  • [24] Hydroxyapatite Coatings Did not Increase TGF-β and BMP-2 Secretion in Murine J774A.1 Macrophages, but Induced a Pro-inflammatory Cytokine Response
    Jakobsen, Stig S.
    Larsen, Agnete
    Stoltenberg, Meredin
    Bruun, Jens M.
    Soballe, Kjeld
    JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2009, 20 (04) : 455 - 465
  • [25] Identification and differential expression of TGF-β1, BMP-2 and activin a responsive genes in pre-osteoblastic cells.
    de Jong, DS
    Bauerschmidt, S
    van Zoelen, EJJ
    Olijve, W
    Steegenga, WT
    JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 : S367 - S367
  • [26] EFFECTS OF LOW-INTENSITY PULSED ULTRASOUND, DEXAMETHASONE/TGF-β1 AND/OR BMP-2 ON THE TRANSCRIPTIONAL EXPRESSION OF GENES IN HUMAN MESENCHYMAL STEM CELLS: CHONDROGENICVS. OSTEOGENIC DIFFERENTIATION
    Lai, Chien-Hung
    Chen, Shih-Ching
    Chiu, Li-Hsuan
    Yang, Charng-Bin
    Tsai, Yu-Hui
    Zuo, Chun S.
    Chang, Walter Hong-Shong
    Lai, Wen-Fu
    ULTRASOUND IN MEDICINE AND BIOLOGY, 2010, 36 (06): : 1022 - 1033
  • [27] Role of p53 in promoting BMP9-induced osteogenic differentiation of mesenchymal stem cells through TGF-β1
    Yao, Xintong
    Li, Peipei
    Deng, Yixuan
    Yang, Yuanyuan
    Luo, Honghong
    He, Baicheng
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2023, 25 (06)
  • [28] TGF-β1-Induced MAPK Activation Promotes Collagen Synthesis, Nodule Formation, Redox Stress and Cellular Senescence in Porcine Aortic Valve Interstitial Cells
    Dasu, Dividutta
    Holmes, Andrew
    Murphy, Geraldine A.
    Mishra, Kumaril
    Rosenkranz, Anke C.
    Horowitz, John D.
    Kennedy, Jennifer A.
    JOURNAL OF HEART VALVE DISEASE, 2013, 22 (05): : 621 - 630
  • [29] Phosphoinositide 3-Kinase (PI3K) Activation is Differentially Regulated during Osteogenesis induced by TGF-β1 and BMP-2/BMP-7
    Yamashita, Haruto
    Ochiai, Hiromi
    Saito, Akiko
    Shintani, Seikou
    Azuma, Toshifumi
    JOURNAL OF HARD TISSUE BIOLOGY, 2014, 23 (01) : 9 - 14
  • [30] siRNA inhibition of MMP9 expression inhibits TGFβ1-induced calcification of aortic valve interstitial cells
    Clark, JN
    Palmatory, E
    Brittin, R
    Narula, NR
    Gorman, J
    Gorman, RC
    Levy, RJ
    MOLECULAR THERAPY, 2004, 9 : S359 - S359