Extracellular Matrix in the Regulation of Stem Cell Differentiation

被引:0
|
作者
E. S. Novoseletskaya
O. A. Grigorieva
A. Yu. Efimenko
N. I. Kalinina
机构
[1] Lomonosov Moscow State University,Institute for Regenerative Medicine, Medical Research and Education Center
[2] Faculty of Medicine,Lomonosov Moscow State University
来源
Biochemistry (Moscow) | 2019年 / 84卷
关键词
extracellular matrix; stem cells; differentiation; stem cell niche; extracellular vesicles; decellularization;
D O I
暂无
中图分类号
学科分类号
摘要
Extracellular matrix (ECM) proteins fill the space between cells in multicellular organisms, contributing to the structure of organs and tissues. The mechanical properties of ECM are well studied. At present, the role of individual ECM components and the three-dimensional tissue-specific matrices in the regulation of cell functional activity, proliferation, migration, acquisition of a specialized phenotype and its maintenance is intensively studied. In this review, we described main ECM structural proteins, enzymes, and extracellular vesicles and present the data on the participation of ECM components in the regulation of stem cell differentiation and self-maintenance, as well as approaches to the modeling of stem cells microenvironment using decellularized ECM.
引用
收藏
页码:232 / 240
页数:8
相关论文
共 50 条
  • [31] Reproductive Stem Cell Differentiation: Extracellular Matrix, Tissue Microenvironment, and Growth Factors Direct the Mesenchymal Stem Cell Lineage Commitment
    Vidane, Atanasio S.
    Zomer, Helena D.
    Oliveira, Bruna M. M.
    Guimaraes, Carina F.
    Fernandes, Claudia B.
    Perecin, Felipe
    Silva, Luciano A.
    Miglino, Maria A.
    Meirelles, Flavio V.
    Ambrosio, Carlos E.
    REPRODUCTIVE SCIENCES, 2013, 20 (10) : 1137 - 1143
  • [32] Reproductive Stem Cell Differentiation: Extracellular Matrix, Tissue Microenvironment, and Growth Factors Direct the Mesenchymal Stem Cell Lineage Commitment
    Atanásio S. Vidane
    Helena D. Zomer
    Bruna M. M. Oliveira
    Carina F. Guimarães
    Cláudia B. Fernandes
    Felipe Perecin
    Luciano A. Silva
    Maria A. Miglino
    Flávio V. Meirelles
    Carlos E. Ambrósio
    Reproductive Sciences, 2013, 20 : 1137 - 1143
  • [33] Extracellular signal regulation of cell differentiation in biofilms
    Liraz Chai
    Hera Vlamakis
    Roberto Kolter
    MRS Bulletin, 2011, 36 : 374 - 379
  • [34] Extracellular signal regulation of cell differentiation in biofilms
    Chai, Liraz
    Vlamakis, Hera
    Kolter, Roberto
    MRS BULLETIN, 2011, 36 (05) : 374 - 379
  • [35] Biophysical Regulation of Stem Cell Differentiation
    Govey, Peter M.
    Loiselle, Alayna E.
    Donahue, Henry J.
    CURRENT OSTEOPOROSIS REPORTS, 2013, 11 (02) : 83 - 91
  • [36] Regulation of Mesenchymal Stem Cell Differentiation
    Cook, David
    Genever, Paul
    TRANSCRIPTIONAL AND TRANSLATIONAL REGULATION OF STEM CELLS, 2013, 786 : 213 - 229
  • [37] Epigenetic Regulation of Stem Cell Differentiation
    Hao Wu
    Yi Eve Sun
    Pediatric Research, 2006, 59 : 21 - 25
  • [38] Biophysical Regulation of Stem Cell Differentiation
    Peter M. Govey
    Alayna E. Loiselle
    Henry J. Donahue
    Current Osteoporosis Reports, 2013, 11 : 83 - 91
  • [39] Epigenetic regulation of stem cell differentiation
    Wu, H
    Sun, YE
    PEDIATRIC RESEARCH, 2006, 59 (04) : 21R - 25R
  • [40] BMP regulation of stem cell differentiation
    Kessler, JA
    Gomes, W
    Guha, U
    Israsena, N
    JOURNAL OF NEUROCHEMISTRY, 2002, 81 : 1 - 1