Lipid peroxidation in erythrocytes of patients with type 2 diabetes mellitus

被引：6

作者：

P. Ashok Kumar

G. Rajagopal

机构：

[1] Annamalai University,Department of Biochemistry, Rajah Muthiah Medical College

来源：

Indian Journal of Clinical Biochemistry | 2003年 / 18卷 / 1期

关键词：

Glutathione; Type 2 Diabetes; Catalase; Peroxidase; Superoxide Dismutase;

D O I：

10.1007/BF02867668

中图分类号：

学科分类号：

摘要：

Lipid peroxidation by measurement of Thiobarbituric Acid Reactive Substances (TBARS) and antioxidant status by determining the activities of the enzymes, Catalase (Cat), Glutathione Peroxidase (GPx) and Superoxide Dismutase (SOD) and the level of Reduced Glutathione (GSH) in the erythrocytes of patients with type 2 Diabetes Mellitus were investigated. It was observed that the level of TBARS in the erythrocytes was increased by 50% showing a significant generation of free radicals in the erythrocytes of these patients. The activities of both Cat and SOD were enhanced while that of GPx was not altered. The level of GSH was also not changed.

引用

页码：71 / 74

页数：3

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