A Perfused In Vitro Human iPSC-Derived Blood–Brain Barrier Faithfully Mimics Transferrin Receptor-Mediated Transcytosis of Therapeutic Antibodies

被引：0
|
作者：
Floriana Burgio
Carine Gaiser
Kevin Brady
Viviana Gatta
Reiner Class
Ramona Schrage
Laura Suter-Dick
机构：
[1] University of Applied Sciences and Arts Northwestern Switzerland (FHNW),Development Sciences
[2] UCB Biopharma SRL,Neuroscience Therapeutic Area
[3] UCB Biopharma SRL,undefined
来源：
Cellular and Molecular Neurobiology | 2023年 / 43卷 / 8期
关键词：
Induced pluripotent stem cells-derived brain microvascular endothelial cells; Microfluidic system; Blood–brain barrier; Receptor-mediated transcytosis; Transferrin receptor; Biologics;
D O I：
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学科分类号：
摘要：
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页码：4173 / 4187
页数：14
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