Protein Spray-Freeze Drying. Effect of Atomization Conditions on Particle Size and Stability

被引:0
|
作者
Henry R Costantino
Laleh Firouzabadian
Ken Hogeland
Chichih Wu
Chris Beganski
Karen G Carrasquillo
Melissa Córdova
Kai Griebenow
Stephen E Zale
Mark A Tracy
机构
[1] Alkermes,Department of Chemistry
[2] Inc.,undefined
[3] Alkermes,undefined
[4] Inc.,undefined
[5] University of Puerto Rico,undefined
来源
Pharmaceutical Research | 2000年 / 17卷
关键词
particle size; PLG microspheres; protein delivery; spray-freeze drying; stability;
D O I
暂无
中图分类号
学科分类号
摘要
Purpose. To investigate the effect of atomization conditions on particle size and stability of spray-freeze dried protein.
引用
收藏
页码:1374 / 1382
页数:8
相关论文
共 50 条
  • [21] Improved storage stability and immunogenicity of hepatitis B vaccine after spray-freeze drying in presence of sugars
    Tonnis, W. F.
    Amorij, J-P
    Vreeman, M. A.
    Frijlink, H. W.
    Kersten, G. F.
    Hinrichs, W. L. J.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2014, 55 : 36 - 45
  • [22] Modelling of influence of turbulent mixing on the course of spray-freeze drying process
    Henczka, Marek
    Baldyga, Jerzy
    INZYNIERIA CHEMICZNA I PROCESOWA, 2006, 27 (02): : 321 - 334
  • [23] Impact of spray-drying conditions on the particle size of microparticulated whey protein fractions
    Toro-Sierra, Jose
    Schumann, Jens
    Kulozik, Ulrich
    DAIRY SCIENCE & TECHNOLOGY, 2013, 93 (4-5) : 487 - 503
  • [24] Thermal inactivation kinetics of microencapsulated microbial transglutaminase by ultrasonic spray-freeze drying
    Isleroglu, Hilal
    Turker, Izzet
    LWT-FOOD SCIENCE AND TECHNOLOGY, 2019, 101 : 653 - 662
  • [25] Spray-freeze-drying for protein powder preparation: Particle characterization and a case study with trypsinogen stability
    Sonner, C
    Maa, YF
    Lee, G
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2002, 91 (10) : 2122 - 2139
  • [26] Poly(lactide-co-glycolide) microsphere formulations of darbepoetin alfa: Spray drying is an alternative to encapsulation by spray-freeze drying
    Burke, PA
    Klumb, LA
    Herberger, JD
    Nguyen, XCC
    Harrell, RA
    Zordich, M
    PHARMACEUTICAL RESEARCH, 2004, 21 (03) : 500 - 506
  • [27] Poly(Lactide-Co-Glycolide) Microsphere Formulations of Darbepoetin Alfa: Spray Drying Is an Alternative to Encapsulation by Spray-Freeze Drying
    Paul A. Burke
    Lisa A. Klumb
    John D. Herberger
    Xichdao C. Nguyen
    Roy A. Harrell
    Monica Zordich
    Pharmaceutical Research, 2004, 21 : 500 - 506
  • [28] Spray freeze drying for protein encapsulation: Impact of the formulation to morphology and stability
    Baldelli, Alberto
    Cidem, Aylin
    Guo, Yigong
    Ong, Hui Xin
    Singh, Anika
    Traini, Daniela
    Pratap-Singh, Anubhav
    DRYING TECHNOLOGY, 2023, 41 (01) : 137 - 150
  • [29] Spray-Freeze Drying: a Suitable Method for Aerosol Delivery of Antibodies in the Presence of Trehalose and Cyclodextrins
    Pouya, Maryam Amini
    Daneshmand, Behnaz
    Aghababaie, Shabnam
    Faghihi, Homa
    Vatanara, Alireza
    AAPS PHARMSCITECH, 2018, 19 (05): : 2247 - 2254
  • [30] Effects of atomization conditions and flow rates on spray drying for cupric chloride particle formation
    Daggupati, V. N.
    Naterer, G. F.
    Gabriel, K. S.
    Gravelsins, R. J.
    Wang, Z. L.
    INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 2011, 36 (17) : 11353 - 11359