Cell-free and intracellular nucleic acids: new non-invasive biomarkers to explore male infertility

被引：0

作者：

Anne Boissière

Anna Gala

Alice Ferrières-Hoa

Tiffany Mullet

Solenne Baillet

Amaël Petiton

Antoine Torre

Samir Hamamah

机构：

[1] CHRU Montpellier,Unité INSERM U1203, Hôpital Saint Eloi

[2] CHRU Montpellier,Département de biologie de la reproduction, Hôpital Arnaud de Villeneuve

来源：

Basic and Clinical Andrology | / 27卷

关键词：

cf-DNA; cf-mRNA; miRNA; piRNA; Male infertility; Seminal plasma; biomarkers; cf-DNA; cf-mRNA; miRNA; piRNA; Infertilité masculine; Plasma séminal; Biomarqueurs;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Male infertility is a devastating problem that affects many couples worldwide. However, the molecular mechanisms and causes of idiopathic male infertility remain unclear. Circulating cell-free nucleic acids have an important role in human physiology and emerging evidence suggests that they play a role in male infertility. This review summarizes recent results on cell-free and intracellular nucleic acids in male infertility and discusses their potential use as biomarkers of male infertility in the clinical practice.

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