Cell-free and intracellular nucleic acids: new non-invasive biomarkers to explore male infertility

被引：0
|
作者：
Anne Boissière
Anna Gala
Alice Ferrières-Hoa
Tiffany Mullet
Solenne Baillet
Amaël Petiton
Antoine Torre
Samir Hamamah
机构：
[1] CHRU Montpellier,Unité INSERM U1203, Hôpital Saint Eloi
[2] CHRU Montpellier,Département de biologie de la reproduction, Hôpital Arnaud de Villeneuve
来源：
Basic and Clinical Andrology | / 27卷
关键词：
cf-DNA; cf-mRNA; miRNA; piRNA; Male infertility; Seminal plasma; biomarkers; cf-DNA; cf-mRNA; miRNA; piRNA; Infertilité masculine; Plasma séminal; Biomarqueurs;
D O I：
暂无
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学科分类号：
摘要：
Male infertility is a devastating problem that affects many couples worldwide. However, the molecular mechanisms and causes of idiopathic male infertility remain unclear. Circulating cell-free nucleic acids have an important role in human physiology and emerging evidence suggests that they play a role in male infertility. This review summarizes recent results on cell-free and intracellular nucleic acids in male infertility and discusses their potential use as biomarkers of male infertility in the clinical practice.
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