Genome-wide association study identifies eight loci associated with blood pressure

被引:0
|
作者
Christopher Newton-Cheh
Toby Johnson
Vesela Gateva
Martin D Tobin
Murielle Bochud
Lachlan Coin
Samer S Najjar
Jing Hua Zhao
Simon C Heath
Susana Eyheramendy
Konstantinos Papadakis
Benjamin F Voight
Laura J Scott
Feng Zhang
Martin Farrall
Toshiko Tanaka
Chris Wallace
John C Chambers
Kay-Tee Khaw
Peter Nilsson
Pim van der Harst
Silvia Polidoro
Diederick E Grobbee
N Charlotte Onland-Moret
Michiel L Bots
Louise V Wain
Katherine S Elliott
Alexander Teumer
Jian'an Luan
Gavin Lucas
Johanna Kuusisto
Paul R Burton
David Hadley
Wendy L McArdle
Morris Brown
Anna Dominiczak
Stephen J Newhouse
Nilesh J Samani
John Webster
Eleftheria Zeggini
Jacques S Beckmann
Sven Bergmann
Noha Lim
Kijoung Song
Peter Vollenweider
Gerard Waeber
Dawn M Waterworth
Xin Yuan
Leif Groop
Marju Orho-Melander
机构
[1] Center for Human Genetic Research,Department of Medical Genetics
[2] Massachusetts General Hospital,Department of Biostatistics and Center for Statistical Genetics
[3] Cardiovascular Research Center,Departments of Health Sciences and Genetics
[4] Massachusetts General Hospital,Department of Epidemiology and Public Health
[5] Program in Medical and Population Genetics,Division of Community Health Sciences
[6] Broad Institute of Harvard and Massachusetts Institute of Technology,Department of Twin Research and Genetic Epidemiology
[7] University of Lausanne,Department of Cardiovascular Medicine
[8] University Institute for Social and Preventative Medicine,Department of Public Health and Primary Care
[9] Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne,Department of Clinical Sciences
[10] Swiss Institute of Bioinformatics,Department of Cardiology
[11] University of Michigan,Department of Medical Genetics
[12] Adrian Building,DBG
[13] University of Leicester,Department of Medicine
[14] Imperial College London,Department of Social Medicine
[15] St. Mary's Campus,Department of Cardiovascular Science
[16] Norfolk Place,Genetics Division
[17] Laboratory of Cardiovascular Science,Department of Internal Medicine
[18] Intramural Research Program,Department of Clinical Sciences
[19] National Institute on Aging,Department of Genetics
[20] National Institutes of Health,Department of Clinical and Experimental Medicine
[21] MRC Epidemiology Unit,Department of Genetics
[22] Institute of Metabolic Science,Department of Epidemiology and Health Promotion
[23] Addenbrooke's Hospital,Cardiovascular Research Center and Cardiology Division
[24] Cambridge-Genetics of Energy Metabolism (GEM) Consortium,Departments of Medicine and Epidemiology
[25] Centre National de Génotypage,Department of Epidemiology
[26] Pontificia Universidad Católica de Chile,Department of Clinical Sciences/Obstetrics and Gynecology
[27] Facultad de Matemáticas,Department of Child and Adolescent Health
[28] Institute of Epidemiology,Division of Nephrology, Department of Medicine
[29] Helmholtz Zentrum München,Department of Epidemiology University Medical Center Groningen
[30] German Research Centre for Environmental Health,Department of Medicine Solna
[31] St. George's,Department of Medical Sciences
[32] University of London,Department of Epidemiology
[33] King's College London,Department of Internal Medicine B
[34] University of Oxford,Department of Public Health
[35] The Wellcome Trust Centre for Human Genetics,Department of Medicine and Department of Genetics
[36] Medstar Research Institute,Department of Biostatistics
[37] Clinical Research Branch,undefined
[38] National Institute on Aging,undefined
[39] Clinical Pharmacology,undefined
[40] William Harvey Research Institute,undefined
[41] Barts and The London School of Medicine and Dentistry,undefined
[42] Queen Mary University of London,undefined
[43] The Genome Centre,undefined
[44] William Harvey Research Institute,undefined
[45] Barts and The London School of Medicine and Dentistry,undefined
[46] Queen Mary University of London,undefined
[47] Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory,undefined
[48] Cambridge Institute for Medical Research University of Cambridge,undefined
[49] Wellcome Trust/MRC Building,undefined
[50] Addenbrooke's Hospital,undefined
来源
Nature Genetics | 2009年 / 41卷
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摘要
Christopher Newton-Cheh and colleagues report a genome-wide association study for blood pressure traits as part of the Global BPgen consortium. They report eight loci with replicated association to systolic and/or diastolic blood pressure, with each also showing association to hypertension.
引用
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页码:666 / 676
页数:10
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