Eco-friendly synthesis of novel thiohydantoin-type sulfur-containing imidazolinone derivatives from glycine ester

被引：0

作者：

Mustafa Kemal Gümüş

Yiannis Elemes

机构：

[1] Artvin Coruh University,Science

[2] University of Ioannina,Technology Research and Application Center

来源：

Chemistry of Heterocyclic Compounds | 2018年 / 54卷

关键词：

glycine ester; imidazolinone thiohydantoin; imidazolone; microwave irradiation; solvent-free synthesis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Imino derivatives of glycine ester were prepared from methyl glycinate by the known procedure and then they reacted with several amines under microwave irradiation without solvent that gave the corresponding glycine amides. By the one-component cyclocondensation, the obtained amide derivatives were transformed into thiohydantoin-type imidazolinones using solvent-free microwave procedure. All imine-ester derivatives and most of the imidazolinone derivatives were synthesized for the first time. This eco-friendly protocol can provide a suitable way for synthesizing new potentially bioactive imidazolinone derivatives.

引用

页码：153 / 157

页数：4

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