Cardiomyopathy in Duchenne muscular dystrophy: pathogenesis and therapeutics

被引:0
|
作者
Abdallah Fayssoil
Olivier Nardi
David Orlikowski
Djillali Annane
机构
[1] University of Medicine and Dentistry of New Jersey,Intensive Care Unit
[2] Raymond Poincaré Hospital,undefined
[3] AP-HP,undefined
来源
Heart Failure Reviews | 2010年 / 15卷
关键词
Duchenne; Dystrophin; Heart failure; ACE inhibitors; Beta-blockers; Experimental therapies;
D O I
暂无
中图分类号
学科分类号
摘要
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by the absence of dystrophin, a sarcolemmal protein which links the cytoskeleton to the extracellular matrix by interacting with a large number of proteins. Heart failure is a classic complication of this disease. The authors review the pathogenesis and therapeutics of cardiac involvement in DMD.
引用
收藏
页码:103 / 107
页数:4
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