A direct method for the synthesis of orthogonally protected furyl- and thienyl- amino acids

被引：0
|
作者：
Alex S. Hudson
Laurent Caron
Neil Colgin
Steven L. Cobb
机构：
[1] Durham University,Department of Chemistry
[2] Cambridge Research Biochemicals Ltd,undefined
来源：
Amino Acids | 2015年 / 47卷
关键词：
Heteroaromatic amino acids; Negishi cross-coupling; Furyl-alanine; Thienyl-alanine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The synthesis of unnatural amino acids plays a key part in expanding the potential application of peptide-based drugs and in the total synthesis of peptide natural products. Herein, we report a direct method for the synthesis of orthogonally protected 5-membered heteroaromatic amino acids.
引用
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页码：779 / 785
页数：6
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