Proteases, proteases and proteases for presentation

被引:0
|
作者
Carla Herberts
Eric Reits
Jacques Neefjes
机构
[1] Netherlands Cancer Institute,Division of Tumor Biology
来源
Nature Immunology | 2003年 / 4卷
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学科分类号
摘要
Peptide epitope generation for MHC class I presentation is normally dependent upon proteasome activity. Yet this pathway fails to generate critical HIV epitopes. Instead, the protease TPPII is required for this activity.
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页码:306 / 308
页数:2
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