Synthesis, molecular modelling and biological activity of some pyridazinone derivatives as selective human monoamine oxidase-B inhibitors

被引：0
|
作者：
Zeynep Özdemir
Mehmet Abdullah Alagöz
Harun Uslu
Arzu Karakurt
Acelya Erikci
Gulberk Ucar
Mehtap Uysal
机构：
[1] Inonu University,Department of Pharmaceutical Chemistry, Faculty of Pharmacy
[2] Vocational School of Health Services,Department of Anesthesiology
[3] Fırat University,Department of Biochemistry, Faculty of Pharmacy
[4] Lokman Hekim University,Department of Pharmaceutical Chemistry, Faculty of Pharmacy
[5] Gazi University,undefined
来源：
Pharmacological Reports | 2020年 / 72卷
关键词：
Pyridazinone; Monoamine oxidase inhibition; Molecular docking;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：692 / 704
页数：12
相关论文
共 50 条
  • [21] EFFECT OF NONSELECTIVE AND SELECTIVE INHIBITORS OF MONOAMINE OXIDASE-A AND OXIDASE-B ON PETHIDINE TOXICITY IN MICE
    BODEN, R
    BOTTING, R
    COULSON, P
    SPANSWICK, G
    BRITISH JOURNAL OF PHARMACOLOGY, 1984, 82 (01) : 151 - 154
  • [22] New class of thio/semicarbazide-based benzyloxy derivatives as selective class of monoamine oxidase-B inhibitors
    Chandran, Namitha
    Lee, Jiseong
    Prabhakaran, Prabitha
    Kumar, Sunil
    Sudevan, Sachithra Thazhathuveedu
    Parambi, Della Grace Thomas
    Alsahli, Tariq G.
    Pant, Manu
    Kim, Hoon
    Mathew, Bijo
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [23] ACETYLENIC AND ALLENIC DERIVATIVES OF 2-(1-METHYLINDOLYL) METHYLAMINE AS SELECTIVE INHIBITORS OF THE MONOAMINE OXIDASE-A AND OXIDASE-B
    CRUCES, MA
    ELORRIAGA, C
    ALVAREZ, EF
    CHICO, MTL
    LOPEZ, ON
    FARMACO-EDIZIONE SCIENTIFICA, 1988, 43 (7-8): : 567 - 573
  • [24] Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity
    Guglielmi, Paolo
    Secci, Daniela
    Petzer, Ariel
    Bagetta, Donatella
    Chimenti, Paola
    Rotondi, Giulia
    Ferrante, Claudio
    Recinella, Lucia
    Leone, Sheila
    Alcaro, Stefano
    Zengin, Gokhan
    Petzer, Jacobus P.
    Ortuso, Francesco
    Carradori, Simone
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2019, 34 (01) : 1511 - 1525
  • [25] DESIGN, SYNTHESIS, AND ENZYMOLOGY OF SOME NOVEL MONOAMINE OXIDASE-B INACTIVATORS
    DING, ZZ
    SILVERMAN, RB
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1992, 203 : 94 - MEDI
  • [26] Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives
    Oh, Jong Min
    Kang, Myung-Gyun
    Hong, Ahreum
    Park, Ji-Eun
    Kim, Soo Hyun
    Lee, Jae Pil
    Baek, Seung Cheol
    Park, Daeui
    Nam, Sang-Jip
    Cho, Myoung-Lae
    Kim, Hoon
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 137 : 426 - 432
  • [27] INHIBITORY POTENCY OF SOME ISATIN ANALOGS ON HUMAN MONOAMINE OXIDASE-A AND OXIDASE-B
    MEDVEDEV, AE
    GOODWIN, B
    CLOW, A
    HALKET, J
    GLOVER, V
    SANDLER, M
    BIOCHEMICAL PHARMACOLOGY, 1992, 44 (03) : 590 - 592
  • [28] SLEEP AND SELECTIVE MONOAMINE OXIDASE-B (MAO-B) INHIBITORS - POSSIBLE CLINICAL CONSEQUENCES
    DZOLJIC, MR
    SLEEP 88, 1989, : 219 - 221
  • [29] Pyrimido[1,2-b]indazole derivatives: Selective inhibitors of human monoamine oxidase B with neuroprotective activity
    Jismy, Badr
    El Qami, Abdelkarim
    Pislar, Anja
    Frlan, Rok
    Kos, Janko
    Gobec, Stanislav
    Knez, Damijan
    Abarbri, Mohamed
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 209
  • [30] Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors
    Gokhan-Kelekci, Nesrin
    Simsek, O. Ozgun
    Ercan, Ayse
    Yelekci, Kemal
    Sahin, Z. Sibel
    Isik, Samil
    Ucar, Guelberk
    Bilgin, A. Altan
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (18) : 6761 - 6772
12345