Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma

被引：0

作者：

Raymond G. Fox

Nikki K. Lytle

Dawn V. Jaquish

Frederick D. Park

Takahiro Ito

Jeevisha Bajaj

Claire S. Koechlein

Bryan Zimdahl

Masato Yano

Janel L. Kopp

Marcie Kritzik

Jason K. Sicklick

Maike Sander

Paul M. Grandgenett

Michael A. Hollingsworth

Shinsuke Shibata

Donald Pizzo

Mark A. Valasek

Roman Sasik

Miriam Scadeng

Hideyuki Okano

Youngsoo Kim

A. Robert MacLeod

Andrew M. Lowy

Tannishtha Reya

机构：

[1] University of California San Diego School of Medicine La Jolla,Department of Pharmacology

[2] University of California San Diego School of Medicine La Jolla,Department of Medicine

[3] Sanford Consortium for Regenerative Medicine,Department of Surgery, Division of Surgical Oncology

[4] Moores Cancer Center,Department of Medicine, Division of Gastroenterology

[5] University of California San Diego School of Medicine,Department of Physiology

[6] University of California San Diego School of Medicine,Department of Cellular and Molecular Medicine

[7] University of California San Diego School of Medicine,Department of Pathology

[8] Keio University School of Medicine,Department of Pathology

[9] University of California San Diego School of Medicine,Department of Radiology

[10] Eppley Institute for Research in Cancer and Allied Diseases,Department of Oncology Drug Discovery

[11] University of Nebraska Medical Center,undefined

[12] University of California San Diego School of Medicine,undefined

[13] Center for Computational Biology and Bioinformatics,undefined

[14] University of California San Diego School of Medicine,undefined

[15] University of California San Diego School of Medicine,undefined

[16] Ionis Pharmaceuticals,undefined

[17] †Present address: Division of Neurobiology and Anatomy,undefined

[18] Graduate School of Medical and Dental Sciences,undefined

[19] Niigata University,undefined

[20] Asahimachidori,undefined

[21] Chuo-ku,undefined

[22] Niigata 951-8510,undefined

[23] Japan.,undefined

来源：

Nature | 2016年 / 534卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The stem cell determinant Musashi (Msi) is a key mediator of pancreatic cancer progression and therapy resistance.

引用

页码：407 / 411

页数：4

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