Mitochondrial DNA in human hair shafts – existence of intra-individual differences?

被引：0
|
作者：
J. Hühne
H. Pfeiffer
K. Waterkamp
B. Brinkmann
机构：
[1] Institute of Forensic Medicine,
[2] University Münster,undefined
[3] von Esmarch Strasse 62,undefined
[4] D-48149 Münster,undefined
[5] Germany,undefined
来源：
International Journal of Legal Medicine | 1999年 / 112卷
关键词：
Key words Mitochondrial DNA; Hypervariable region 1; DNA extraction; Human hair shafts; Heteroplasmy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The sequences of the hypervariable region 1 (HV1) of the mitochondrial DNA control region from multiple hair shafts from 10 unrelated individuals were compared to determine the frequency of differences in hairs from one individual. The extraction method described herein showed an average success rate of 67% for all 150 hair shafts tested in HV1. The mtDNA sequences from the hair shafts matched the sequences from the corresponding blood and saliva samples taken from the same donor and no evidence of heteroplasmy was found. The results emphasize the reliability of DNA extraction and mtDNA typing from human hair shafts for forensic purposes.
引用
收藏
页码：172 / 175
页数：3
相关论文
共 50 条
  • [31] Utility of hair shafts from study skins for mitochondrial DNA analysis
    Kurihara, N.
    GENETICS AND MOLECULAR RESEARCH, 2013, 12 (04): : 5396 - 5404
  • [32] Inter-individual differences in intra-individual variability in personality within and across contexts
    Beckmann, Nadin
    Birney, Damian P.
    Beckmann, Jens F.
    Wood, Robert E.
    Sojo, Victor
    Bowman, David
    JOURNAL OF RESEARCH IN PERSONALITY, 2020, 85
  • [33] REMINISCENCE EFFECTS ON INTER-INDIVIDUAL AND INTRA-INDIVIDUAL DIFFERENCES IN PURSUIT ROTOR PERFORMANCE
    ALDERMAN, RB
    RESEARCH QUARTERLY, 1968, 39 (03): : 423 - 427
  • [34] Multi-factor analysis of inter-individual differences in intra-individual changes
    Zimprich, D.
    ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE, 2010, 43 : 10 - 10
  • [35] Inter-individual vs intra-individual differences: An important distinction for shiftwork research?
    Tepas, D
    Pratt, J
    Howarth, H
    SHIFTWORK IN THE 21ST CENTURY: CHALLENGES FOR RESEARCH AND PRACTICE, 2000, 17 : 273 - 279
  • [36] Investigating Inter-Individual Differences in Short-Term Intra-Individual Variability
    Wang, Lijuan
    Hamaker, Ellen
    Bergeman, C. S.
    PSYCHOLOGICAL METHODS, 2012, 17 (04) : 567 - 581
  • [37] Lateralisation and cancer; Reflections on intra-individual developmental differences on cancer risk
    VanNoord, P. A. H.
    Garcia-Sagredo, J. M.
    Van Dijck, J. A. A. M.
    EUROPEAN JOURNAL OF EPIDEMIOLOGY, 2006, 21 : 124 - 124
  • [38] INTRA-INDIVIDUAL DIFFERENCES IN SUSCEPTIBILITY TO THE SOUND-INDUCED FLASH ILLUSION
    Chan, Jason
    Connolly, Shannon
    Setti, Annalisa
    AGE AND AGEING, 2016, 45 : 42 - 42
  • [39] Intra-individual differences and relationship-specificity of mentalising in early adolescence
    O'Connor, TG
    Hirsch, N
    SOCIAL DEVELOPMENT, 1999, 8 (02) : 256 - 274
  • [40] INTER- AND INTRA-INDIVIDUAL DIFFERENCES IN ENERGY EXPENDITURE AND MECHANICAL EFFICIENCY
    WYNDHAM, CH
    MORRISON, JF
    WILLIAMS, CG
    STRYDOM, NB
    VONRAHDE.MJ
    HOLDSWORTH, LD
    VANGRAAN, CH
    VANRENSB.AJ
    JOFFE, A
    HEYNS, A
    ERGONOMICS, 1966, 9 (01) : 17 - +
12345