Unleashing CAR T cells to delay metabolic aging

被引：0

作者：

Jenna M. Bartley

Ming Xu

机构：

[1] UConn Health,UConn Center on Aging

[2] UConn Health,Department of Immunology

[3] UConn Health,Department of Genetics and Genome Sciences

来源：

Nature Aging | 2024年 / 4卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Amor and colleagues previously developed chimeric antigen receptor (CAR) T cells that can target and eliminate senescent cells. The utility of these senolytic CAR T cells is now expanded to show that they can combat age-related metabolic dysfunction, and that they can be used prophylactically and have effects that persist for months, thus opening the door to the development of long-term senolytic approaches.

引用

页码：284 / 286

页数：2

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