机构:Harvard University,Department of Human Evolutionary Biology
Rachel N. Carmody
Jordan E. Bisanz
论文数: 0引用数: 0
h-index: 0
机构:Harvard University,Department of Human Evolutionary Biology
Jordan E. Bisanz
机构:
[1] Harvard University,Department of Human Evolutionary Biology
[2] The Pennsylvania State University,Department of Biochemistry and Molecular Biology, Penn State Microbiome Center, Huck Institutes of the Life Sciences
Overweight, obesity, undernutrition and their respective sequelae have devastating tolls on personal and public health worldwide. Traditional approaches for treating these conditions with diet, exercise, drugs and/or surgery have shown varying degrees of success, creating an urgent need for new solutions with long-term efficacy. Owing to transformative advances in sequencing, bioinformatics and gnotobiotic experimentation, we now understand that the gut microbiome profoundly impacts energy balance through diverse mechanisms affecting both sides of the energy balance equation. Our growing knowledge of microbial contributions to energy metabolism highlights new opportunities for weight management, including the microbiome-aware improvement of existing tools and novel microbiome-targeted therapies. In this Review, we synthesize current knowledge concerning the bidirectional influences between the gut microbiome and existing weight management strategies, including behaviour-based and clinical approaches, and incorporate a subject-level meta-analysis contrasting the effects of weight management strategies on microbiota composition. We consider how emerging understanding of the gut microbiome alters our prospects for weight management and the challenges that must be overcome for microbiome-focused solutions to achieve success.
机构:
City Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
City Univ Hong Kong, Tung Biomed Sci Ctr, Hong Kong, Peoples R ChinaCity Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
Bui, Thi Van Anh
Hwangbo, Hyesoo
论文数: 0引用数: 0
h-index: 0
机构:
City Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
City Univ Hong Kong, Tung Biomed Sci Ctr, Hong Kong, Peoples R ChinaCity Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
Hwangbo, Hyesoo
Lai, Yimin
论文数: 0引用数: 0
h-index: 0
机构:
City Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
City Univ Hong Kong, Tung Biomed Sci Ctr, Hong Kong, Peoples R ChinaCity Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
Lai, Yimin
Hong, Seok Beom
论文数: 0引用数: 0
h-index: 0
机构:
Catholic Univ Korea, Dept Thorac & Cardiovasc Surg, Seoul St Marys Hosp, Coll Med, Seoul, South KoreaCity Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
Hong, Seok Beom
Choi, Yeon-Jik
论文数: 0引用数: 0
h-index: 0
机构:
Catholic Univ Korea, Div Cardiol, Dept Internal Med, Eunpyeong St Marys Hosp,Coll Med, Seoul, South KoreaCity Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
Choi, Yeon-Jik
论文数: 引用数:
h-index:
机构:
Park, Hun-Jun
Ban, Kiwon
论文数: 0引用数: 0
h-index: 0
机构:
City Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
City Univ Hong Kong, Tung Biomed Sci Ctr, Hong Kong, Peoples R China
City Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Kowloon Tong, 83 Tat Chee Ave, Hong Kong, Peoples R ChinaCity Univ Hong Kong, Coll Vet Med & Life Sci, Dept Biomed Sci, Hong Kong, Peoples R China
机构:Harvard Med Sch, Boston Childrens Hosp, Dept Microbiol, Dept Pediat,Div Infect Dis, Boston, MA 02115 USA
Kuziel, Gavin A.
Rakoff-Nahoum, Seth
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Med Sch, Boston Childrens Hosp, Dept Microbiol, Dept Pediat,Div Infect Dis, Boston, MA 02115 USAHarvard Med Sch, Boston Childrens Hosp, Dept Microbiol, Dept Pediat,Div Infect Dis, Boston, MA 02115 USA
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiangsu Prov Acad Tradit Chinese Med, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiang, Ziyu
Li, Lingchang
论文数: 0引用数: 0
h-index: 0
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiangsu Prov Acad Tradit Chinese Med, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Li, Lingchang
Chen, Jianan
论文数: 0引用数: 0
h-index: 0
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Chen, Jianan
Wei, Guoli
论文数: 0引用数: 0
h-index: 0
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiangsu Prov Acad Tradit Chinese Med, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Wei, Guoli
Ji, Yi
论文数: 0引用数: 0
h-index: 0
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiangsu Prov Acad Tradit Chinese Med, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Ji, Yi
Chen, Xi
论文数: 0引用数: 0
h-index: 0
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiangsu Prov Acad Tradit Chinese Med, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Chen, Xi
Liu, Jingbing
论文数: 0引用数: 0
h-index: 0
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiangsu Prov Acad Tradit Chinese Med, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Liu, Jingbing
Huo, Jiege
论文数: 0引用数: 0
h-index: 0
机构:
Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China
Jiangsu Prov Acad Tradit Chinese Med, Nanjing 210028, Peoples R ChinaNanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Oncol, Nanjing 210028, Peoples R China