A multi-omics roadmap of β-cell failure in type 2 diabetes mellitus

被引：0
|
作者：
Gaowei Wang
Maike Sander
机构：
[1] University of California San Diego,Department of Pediatrics, Pediatric Diabetes Research Center
来源：
Nature Reviews Endocrinology | 2021年 / 17卷
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学科分类号：
摘要：
Pancreatic β-cell dysfunction contributes to type 2 diabetes mellitus (T2DM) pathogenesis. However, human islet studies have revealed few consistent molecular changes in T2DM, owing partly to technical and biological confounding factors. A new multi-omics study of islets from well-phenotyped living donors attempts to overcome these limitations to catalogue T2DM-associated molecular changes.
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页码：641 / 642
页数：1
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