Synthesis and biological activity of new pyranochromen-3-carboxamides

被引：0
|
作者：
R. V. Shutov
E. V. Kuklina
N. A. Anisimova
E. P. Anan’ev
N. I. Kotova
V. N. Kuklin
机构：
[1] St. Petersburg State Chemico-Pharmaceutical Academy,
来源：
Pharmaceutical Chemistry Journal | 2012年 / 46卷
关键词：
pyranochromen-3-carboxamides; 3-formylchromones; synthesis; structure; analgesic; anxiolytic; and antimicrobial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A series of new pyranochromen-3-carboxamides have been synthesized in good yield by reacting 2-phenyl-4-hydroxy-6H-1,3-thiazin-6-ones with substituted 3-formylchromones. Pharmacological screening showed an influence of the substituent in the 9-position of the pyranochromen-3-carboxamides on the acute toxicity and antifungal, analgesic, and anxiolytic activity. 9-Bromo-2H,5H-pyranochromen-3-carboxamide can be recommended for further pharmacological investigation.
引用
收藏
页码：10 / 14
页数：4
相关论文
共 50 条
  • [41] Synthesis and biological activity of new metronidazole derivatives
    Al-Masoudi, Najim A.
    Abbas, Zina A. A.
    MONATSHEFTE FUR CHEMIE, 2016, 147 (02): : 383 - 390
  • [42] Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides
    Semelkova, Lucia
    Konecna, Klara
    Paterova, Pavla
    Kubicek, Vladimir
    Kunes, Jiri
    Novakova, Lucie
    Marek, Jan
    Naesens, Lieve
    Pesko, Matus
    Kralova, Katarina
    Dolezal, Martin
    Zitko, Jan
    MOLECULES, 2015, 20 (05): : 8687 - 8711
  • [43] Synthesis and Evaluation of Biological Activity of New Arylphosphoramidates
    Thebti, Amal
    Sanhoury, M. A. K.
    Ouzari, H-I.
    Barhoumi-slimi, T.
    BIOMED RESEARCH INTERNATIONAL, 2018, 2018
  • [44] Synthesis and biological activity of new pyrazolines and pyrazoles
    Basaif, SA
    Faidallah, HM
    Hasan, SY
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 1996, 6 (01) : 53 - 58
  • [45] Synthesis and biological activity of some new benzoxazoles
    Temiz-Arpaci, Oezlem
    Yildiz, Ilkay
    Oezkan, Semiha
    Kaynak, Fatma
    Aki-Sener, Esin
    Yalcin, Ismail
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (07) : 1423 - 1431
  • [46] Synthesis and biological activity of new phenylsulfonylurea derivatives
    Ma, N
    Li, PF
    Li, YH
    Li, ZM
    Wang, LX
    Wang, SH
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2004, 25 (12): : 2259 - 2262
  • [47] Synthesis and biological activity of new metronidazole derivatives
    Najim A. Al-Masoudi
    Zina A. A. Abbas
    Monatshefte für Chemie - Chemical Monthly, 2016, 147 : 383 - 390
  • [48] SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW TRIAZOLYLBENZODIAZEPINES
    Kalluraya, B.
    Mallya, Sahana
    Asma
    Aparna, K.
    Kaushik, B. R.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2016, 26 (3-4) : 121 - 125
  • [49] Synthesis and biological activity of some new pyrimidines
    Moustafa, HY
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 1998, 7 (04) : 273 - 276
  • [50] New Analogues of Acyclovir - Synthesis and Biological Activity
    Stankova, Ivanka
    Schichkov, Stovan
    Kostova, Kalina
    Galabov, Angel
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, 2010, 65 (1-2): : 29 - 33
12345