How distinct Arp2/3 complex variants regulate actin filament assembly

被引:0
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作者
Klemens Rottner
Theresia E. B. Stradal
机构
[1] Klemens Rottner and Theresia E. B. Stradal are at the Helmholtz Centre for Infection Research,
[2] Inhoffenstrasse 7,undefined
[3] 38124 Braunschweig,undefined
[4] Germany,undefined
[5] Klemens Rottner is also at the Zoological Institute,undefined
[6] Technische Universität Braunschweig,undefined
[7] Spielmannstrasse 7,undefined
[8] 38106 Braunschweig,undefined
[9] Germany,undefined
来源
Nature Cell Biology | 2016年 / 18卷
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摘要
The heptameric Arp2/3 complex generates branched actin filament networks that drive lamellipodium protrusion, vesicle trafficking and pathogen motility. Distinct variants of the Arp2/3 complex are now shown to have different roles in tuning actin assembly and disassembly, in concert with the prominent actin regulators cortactin and coronin.
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页码:1 / 3
页数:2
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