A pilot study of regenerative therapy using controlled release of recombinant human fibroblast growth factor for patients with pre-collapse osteonecrosis of the femoral head

被引：0
|
作者：
Yutaka Kuroda
Ryuta Asada
Kazutaka So
Atsushi Yonezawa
Manabu Nankaku
Kumi Mukai
Toshiko Ito-Ihara
Harue Tada
Michio Yamamoto
Toshinori Murayama
Satoshi Morita
Yasuhiko Tabata
Masayuki Yokode
Akira Shimizu
Shuichi Matsuda
Haruhiko Akiyama
机构：
[1] Kyoto University,Department of Orthopaedic Surgery, Graduate School of Medicine
[2] Gifu University Hospital,Clinical Research Center
[3] Kyoto University Hospital,Department of Clinical Pharmacology and Therapeutics
[4] Kyoto University Hospital,Rehabilitation Unit
[5] Kyoto University Hospital,Department of Clinical Innovative Medicine, Institute for Advancement of Clinical and Translational Research (iACT)
[6] Kyoto University Hospital,Department of Data Science, Institute for Advancement of Clinical and Translational Research (iACT)
[7] Kyoto University Hospital,Department of Experimental Therapeutics, Institute for Advancement of Clinical and Translational Research (iACT)
[8] Kyoto University,Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences
[9] Gifu University,Department of Orthopaedic Surgery
来源：
International Orthopaedics | 2016年 / 40卷
关键词：
Clinical trial; Femoral head; FGF; Growth factor; Osteonecrosis; Regenerative therapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1747 / 1754
页数：7
相关论文
共 50 条
  • [31] Minimal pre-operative leg length discrepancy as a risk factor of post-operative leg length discrepancy after total hip arthroplasty: a retrospective study of patients with non-traumatic osteonecrosis of the femoral head
    Kim, Hong Seok
    Lee, Han Jin
    Yoo, Jeong Joon
    BMC MUSCULOSKELETAL DISORDERS, 2023, 24 (01)
  • [32] A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia
    Schiffer, CA
    Miller, K
    Larson, RA
    Amrein, PC
    Antin, JH
    Zani, VJ
    Stone, RM
    BLOOD, 2000, 95 (08) : 2530 - 2535
  • [33] Intramyocardial plasmid-encoding human vascular endothelial growth factor A165/basic fibroblast growth factor therapy using percutaneous transcatheter approach in patients with refractory coronary artery disease (VIF-CAD)
    Kukula, Krzysztof
    Chojnowska, Lidia
    Dabrowski, Maciej
    Witkowski, Adam
    Chmielak, Zbigniew
    Skwarek, Miroslaw
    Kadziela, Jacek
    Teresinska, Anna
    Malecki, Maciej
    Janik, Przemyslaw
    Lewandowski, Zbigniew
    Klopotowski, Mariusz
    Wnuk, Jacek
    Ruzyllo, Witold
    AMERICAN HEART JOURNAL, 2011, 161 (03) : 581 - 589
  • [34] Randomized, multicenter, double-blind, and placebo-controlled trial using topical recombinant human acidic fibroblast growth factor for deep partial-thickness burns and skin graft donor site
    Bing, Ma
    Da-Sheng, Cheng
    Zhao-Fan, Xia
    Dao-Feng, Ben
    Wei, Lu
    Zhi-Fang, Cao
    Qiang, Wang
    Jia, He
    Jia-Ke, Chai
    Chuan-An, Shen
    Yong-Hua, Sun
    Guo-An, Zhang
    Xiao-Hua, Hu
    WOUND REPAIR AND REGENERATION, 2007, 15 (06) : 795 - 799
  • [35] Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: A double-blind, placebo-controlled pilot study
    Boonen, S
    Rosen, C
    Bouillon, R
    Sommer, A
    McKay, M
    Rosen, D
    Adams, S
    Broos, P
    Lenaerts, J
    Raus, J
    Vanderschueren, D
    Geusens, P
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (04): : 1593 - 1599
  • [36] The therapeutic effect of recombinant human epidermal growth factor (rhEGF) on mucositis in patients with head and neck cancer undergoing radiotherapy with or without chemotherapy: a double-blind placebo-controlled prospective phase II multi-institutional study
    Ahn, Y.
    Wu, H.
    Song, S.
    Kim, Y.
    Oh, Y.
    Lee, C.
    Keum, K.
    Lee, S.
    JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
  • [37] A Randomized Controlled Trial of Palifermin (Recombinant Human Keratinocyte Growth Factor) for the Treatment of Inadequate CD4+ T-Lymphocyte Recovery in Patients with HIV-1 Infection on Antiretroviral Therapy
    Jacobson, Jeffrey M.
    Wang, Hongying
    Bordi, Rebeka
    Zheng, Lu
    Gross, Barry H.
    Landay, Alan L.
    Spritzler, John
    Routy, Jean-Pierre
    Benson, Constance
    Aberg, Judith
    Tebas, Pablo
    Haas, David W.
    Tiu, Jennifer
    Coughlin, Kristine
    Purdue, Lynette
    Sekaly, Rafick-Pierre
    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2014, 66 (04) : 399 - 406
  • [38] Surgical Periodontal Therapy Using Recombinant Human Fibroblast Growth Factor-2 in Combination with Carbonate Apatite Granules for Stage III Grade B Periodontitis: A Case Report with 1-year Follow-up
    Murakami, Tasuku
    Imamura, Kentaro
    Watanabe-Egawa, Naoko
    Tomita, Sachiyo
    Saito, Atsushi
    BULLETIN OF TOKYO DENTAL COLLEGE, 2022, 63 (03): : 145 - 153
  • [39] Novel approach to therapeutic angiogenesis for patients with critical limb ischemia by sustained release of basic fibroblast growth factor using biodegradable gelatin hydrogel - An initial report of the phase I-IIa study
    Marui, Akira
    Tabata, Yasuhiko
    Kojima, Shinsuke
    Yamamoto, Masaya
    Tambara, Keiichi
    Nishina, Takeshi
    Saji, Yoshiaki
    Inui, Ken-ichi
    Hashida, Tohru
    Yokoyama, Sumiko
    Onodera, Rie
    Ikeda, Tadashi
    Fukushima, Masanori
    Komeda, Masashi
    CIRCULATION JOURNAL, 2007, 71 (08) : 1181 - 1186
  • [40] Insulin-like growth factor-I (IGF-I) therapy in patients with advanced liver cirrhosis. Results of a randomized double-blind, controlled pilot study.
    Conchillo, M
    de Knegt, R
    Payeras, M
    Quiroga, J
    Sangro, B
    Herrero, I
    Yoshizawa, C
    Jansen, P
    Scharschmidt, B
    Prieto, J
    HEPATOLOGY, 2003, 38 (04) : 604A - 604A
12345